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Sildenafil is a strong and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), that's chargeable for degradation of cGMP in the corpus cavernosum. The molecular framework of sildenafil is comparable to that of cGMP and acts as being a aggressive binding agent of PDE5 during the corpus cavernosum, leading to far more cGMP and enhan